TOP GUIDELINES OF PKRRATING

3B). R526 in the loop among αJ and αI anchors the C-terminal portion of the activation loop by forming a salt bridge with E458 at The bottom of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the leading chain carbonyl of R413. The suggestion of the activation section is stabilized by a hydrogen bond among Y454 and E480 from αfile. whi